Computer-Aided Identification of Trypanosoma brucei Uridine Diphosphate Galactose 4′-Epimerase Inhibitors: Toward the Development of Novel Therapies for African Sleeping Sickness

[Image: see text] Trypanosoma brucei, the causative agent of human African trypanosomiasis, affects tens of thousands of sub-Saharan Africans. As current therapeutics are inadequate due to toxic side effects, drug resistance, and limited effectiveness, novel therapies are urgently needed. UDP-galact...

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Detalles Bibliográficos
Autores principales: Durrant, Jacob D., Urbaniak, Michael D., Ferguson, Michael A. J., McCammon, J. Andrew
Formato: Texto
Lenguaje:English
Publicado: American Chemical Society 2010
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2895357/
https://www.ncbi.nlm.nih.gov/pubmed/20527952
http://dx.doi.org/10.1021/jm100456a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2895357/
https://www.ncbi.nlm.nih.gov/pubmed/20527952
http://dx.doi.org/10.1021/jm100456a

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