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Intestinal stem cells lacking the Math1 tumour suppressor are refractory to Notch inhibitors
Intestinal cells are constantly produced from a stem cell reservoir that gives rise to proliferating transient amplifying cells, which subsequently differentiate into one of the four principal cell types. Signalling pathways, including the Notch signalling pathway, coordinate these differentiation p...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2895507/ https://www.ncbi.nlm.nih.gov/pubmed/20975679 http://dx.doi.org/10.1038/ncomms1017 |