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Effects of Macromolecular Crowding on Protein Conformational Changes

Many protein functions can be directly linked to conformational changes. Inside cells, the equilibria and transition rates between different conformations may be affected by macromolecular crowding. We have recently developed a new approach for modeling crowding effects, which enables an atomistic r...

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Detalles Bibliográficos
Autores principales: Dong, Hao, Qin, Sanbo, Zhou, Huan-Xiang
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2895631/
https://www.ncbi.nlm.nih.gov/pubmed/20617196
http://dx.doi.org/10.1371/journal.pcbi.1000833