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Effects of Macromolecular Crowding on Protein Conformational Changes
Many protein functions can be directly linked to conformational changes. Inside cells, the equilibria and transition rates between different conformations may be affected by macromolecular crowding. We have recently developed a new approach for modeling crowding effects, which enables an atomistic r...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2895631/ https://www.ncbi.nlm.nih.gov/pubmed/20617196 http://dx.doi.org/10.1371/journal.pcbi.1000833 |