The Energy Landscape, Folding Pathways and the Kinetics of a Knotted Protein

The folding pathway and rate coefficients of the folding of a knotted protein are calculated for a potential energy function with minimal energetic frustration. A kinetic transition network is constructed using the discrete path sampling approach, and the resulting potential energy surface is visual...

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Detalles Bibliográficos
Autores principales: Prentiss, Michael C., Wales, David J., Wolynes, Peter G.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2895632/
https://www.ncbi.nlm.nih.gov/pubmed/20617197
http://dx.doi.org/10.1371/journal.pcbi.1000835

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2895632/
https://www.ncbi.nlm.nih.gov/pubmed/20617197
http://dx.doi.org/10.1371/journal.pcbi.1000835

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