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The Energy Landscape, Folding Pathways and the Kinetics of a Knotted Protein
The folding pathway and rate coefficients of the folding of a knotted protein are calculated for a potential energy function with minimal energetic frustration. A kinetic transition network is constructed using the discrete path sampling approach, and the resulting potential energy surface is visual...
Autores principales: | Prentiss, Michael C., Wales, David J., Wolynes, Peter G. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2895632/ https://www.ncbi.nlm.nih.gov/pubmed/20617197 http://dx.doi.org/10.1371/journal.pcbi.1000835 |
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