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Cohesin Is Limiting for the Suppression of DNA Damage–Induced Recombination between Homologous Chromosomes

Double-strand break (DSB) repair through homologous recombination (HR) is an evolutionarily conserved process that is generally error-free. The risk to genome stability posed by nonallelic recombination or loss-of-heterozygosity could be reduced by confining HR to sister chromatids, thereby preventi...

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Detalles Bibliográficos
Autores principales: Covo, Shay, Westmoreland, James W., Gordenin, Dmitry A., Resnick, Michael A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2895640/
https://www.ncbi.nlm.nih.gov/pubmed/20617204
http://dx.doi.org/10.1371/journal.pgen.1001006