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Cohesin Is Limiting for the Suppression of DNA Damage–Induced Recombination between Homologous Chromosomes
Double-strand break (DSB) repair through homologous recombination (HR) is an evolutionarily conserved process that is generally error-free. The risk to genome stability posed by nonallelic recombination or loss-of-heterozygosity could be reduced by confining HR to sister chromatids, thereby preventi...
Autores principales: | Covo, Shay, Westmoreland, James W., Gordenin, Dmitry A., Resnick, Michael A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2895640/ https://www.ncbi.nlm.nih.gov/pubmed/20617204 http://dx.doi.org/10.1371/journal.pgen.1001006 |
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