Comparative Analysis of DNA Replication Timing Reveals Conserved Large-Scale Chromosomal Architecture

Recent evidence suggests that the timing of DNA replication is coordinated across megabase-scale domains in metazoan genomes, yet the importance of this aspect of genome organization is unclear. Here we show that replication timing is remarkably conserved between human and mouse, uncovering large re...

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Detalles Bibliográficos
Autores principales: Yaffe, Eitan, Farkash-Amar, Shlomit, Polten, Andreas, Yakhini, Zohar, Tanay, Amos, Simon, Itamar
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2895651/
https://www.ncbi.nlm.nih.gov/pubmed/20617169
http://dx.doi.org/10.1371/journal.pgen.1001011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2895651/
https://www.ncbi.nlm.nih.gov/pubmed/20617169
http://dx.doi.org/10.1371/journal.pgen.1001011

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