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Comparative Analysis of DNA Replication Timing Reveals Conserved Large-Scale Chromosomal Architecture
Recent evidence suggests that the timing of DNA replication is coordinated across megabase-scale domains in metazoan genomes, yet the importance of this aspect of genome organization is unclear. Here we show that replication timing is remarkably conserved between human and mouse, uncovering large re...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2895651/ https://www.ncbi.nlm.nih.gov/pubmed/20617169 http://dx.doi.org/10.1371/journal.pgen.1001011 |