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PPARγ and LXR Signaling Inhibit Dendritic Cell-Mediated HIV-1 Capture and trans-Infection

Dendritic cells (DCs) contribute to human immunodeficiency virus type 1 (HIV-1) transmission and dissemination by capturing and transporting infectious virus from the mucosa to draining lymph nodes, and transferring these virus particles to CD4+ T cells with high efficiency. Toll-like receptor (TLR)...

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Detalles Bibliográficos
Autores principales: Hanley, Timothy M., Blay Puryear, Wendy, Gummuluru, Suryaram, Viglianti, Gregory A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2895661/
https://www.ncbi.nlm.nih.gov/pubmed/20617179
http://dx.doi.org/10.1371/journal.ppat.1000981