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Bid Regulates the Pathogenesis of Neurotropic Reovirus

Reovirus infection leads to apoptosis in both cultured cells and the murine central nervous system (CNS). NF-κB-driven transcription of proapoptotic cellular genes is required for the effector phase of the apoptotic response. Although both extrinsic death-receptor signaling pathways and intrinsic pa...

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Detalles Bibliográficos
Autores principales: Danthi, Pranav, Pruijssers, Andrea J., Berger, Angela K., Holm, Geoffrey H., Zinkel, Sandra S., Dermody, Terence S.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2895667/
https://www.ncbi.nlm.nih.gov/pubmed/20617182
http://dx.doi.org/10.1371/journal.ppat.1000980