PIP(2)-Binding Site in Kir Channels: Definition by Multiscale Biomolecular Simulations

[Image: see text] Phosphatidylinositol bisphosphate (PIP(2)) is an activator of mammalian inwardly rectifying potassium (Kir) channels. Multiscale simulations, via a sequential combination of coarse-grained and atomistic molecular dynamics, enabled exploration of the interactions of PIP(2) molecules...

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Detalles Bibliográficos
Autores principales: Stansfeld, Phillip J., Hopkinson, Richard, Ashcroft, Frances M., Sansom, Mark S. P.
Formato: Texto
Lenguaje:English
Publicado: American Chemical Society 2009
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2895862/
https://www.ncbi.nlm.nih.gov/pubmed/19839652
http://dx.doi.org/10.1021/bi9013193

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2895862/
https://www.ncbi.nlm.nih.gov/pubmed/19839652
http://dx.doi.org/10.1021/bi9013193

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