Cloning large natural product gene clusters from the environment: Piecing environmental DNA gene clusters back together with TAR

A single gram of soil can contain thousands of unique bacterial species, of which only a small fraction is regularly cultured in the laboratory. Although the fermentation of cultured microorganisms has provided access to numerous bioactive secondary metabolites, with these same methods it is not pos...

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Detalles Bibliográficos
Autores principales: Kim, Jeffrey H, Feng, Zhiyang, Bauer, John D, Kallifidas, Dimitris, Calle, Paula Y, Brady, Sean F
Formato: Texto
Lenguaje:English
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2010
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2895911/
https://www.ncbi.nlm.nih.gov/pubmed/20577994
http://dx.doi.org/10.1002/bip.21450

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2895911/
https://www.ncbi.nlm.nih.gov/pubmed/20577994
http://dx.doi.org/10.1002/bip.21450

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