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i-GSEA4GWAS: a web server for identification of pathways/gene sets associated with traits by applying an improved gene set enrichment analysis to genome-wide association study

Genome-wide association study (GWAS) is nowadays widely used to identify genes involved in human complex disease. The standard GWAS analysis examines SNPs/genes independently and identifies only a number of the most significant SNPs. It ignores the combined effect of weaker SNPs/genes, which leads t...

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Detalles Bibliográficos
Autores principales: Zhang, Kunlin, Cui, Sijia, Chang, Suhua, Zhang, Liuyan, Wang, Jing
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2896119/
https://www.ncbi.nlm.nih.gov/pubmed/20435672
http://dx.doi.org/10.1093/nar/gkq324