Cargando…
DrugScore(PPI) webserver: fast and accurate in silico alanine scanning for scoring protein–protein interactions
Protein–protein complexes play key roles in all cellular signal transduction processes. We have developed a fast and accurate computational approach to predict changes in the binding free energy upon alanine mutations in protein–protein interfaces. The approach is based on a knowledge-based scoring...
| Autores principales: | , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2010
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2896140/ https://www.ncbi.nlm.nih.gov/pubmed/20511591 http://dx.doi.org/10.1093/nar/gkq471 |