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Analysis of vkorc1 polymorphisms in Norway rats using the roof rat as outgroup
BACKGROUND: Certain mutations in the vitamin K epoxide reductase subcomponent 1 gene (vkorc1) mediate rodent resistance to warfarin and other anticoagulants. Testing for resistance often involves analysis of the vkorc1. However, a genetic test for the roof rat (Rattus rattus) has yet to be developed...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2896334/ https://www.ncbi.nlm.nih.gov/pubmed/20497562 http://dx.doi.org/10.1186/1471-2156-11-43 |