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Analysis of vkorc1 polymorphisms in Norway rats using the roof rat as outgroup

BACKGROUND: Certain mutations in the vitamin K epoxide reductase subcomponent 1 gene (vkorc1) mediate rodent resistance to warfarin and other anticoagulants. Testing for resistance often involves analysis of the vkorc1. However, a genetic test for the roof rat (Rattus rattus) has yet to be developed...

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Detalles Bibliográficos
Autores principales: Díaz, Juan C, Song, Ying, Moore, Anthony, Borchert, Jeff N, Kohn, Michael H
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2896334/
https://www.ncbi.nlm.nih.gov/pubmed/20497562
http://dx.doi.org/10.1186/1471-2156-11-43