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Acquired Antibody Responses against Plasmodium vivax Infection Vary with Host Genotype for Duffy Antigen Receptor for Chemokines (DARC)

BACKGROUND: Polymorphism of the Duffy Antigen Receptor for Chemokines (DARC) is associated with susceptibility to and the severity of Plasmodium vivax malaria in humans. P. vivax uses DARC to invade erythrocytes. Individuals lacking DARC are ‘resistant’ to P. vivax erythrocytic infection. However, s...

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Detalles Bibliográficos
Autores principales: Maestre, Amanda, Muskus, Carlos, Duque, Victoria, Agudelo, Olga, Liu, Pu, Takagi, Akihide, Ntumngia, Francis B., Adams, John H., Sim, Kim Lee, Hoffman, Stephen L., Corradin, Giampietro, Velez, Ivan D., Wang, Ruobing
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2896388/
https://www.ncbi.nlm.nih.gov/pubmed/20664684
http://dx.doi.org/10.1371/journal.pone.0011437