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Double Negative (CD3(+)4(−)8(−)) TCRαβ Splenic Cells from Young NOD Mice Provide Long-Lasting Protection against Type 1 Diabetes

BACKGROUND: Double negative CD3(+)4(−)8(−) TCRαβ splenic cells (DNCD3) can suppress the immune responses to allo and xenografts, infectious agents, tumors, and some autoimmune disorders. However, little is known about their role in autoimmune diabetes, a disease characterized by the reduction of ins...

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Detalles Bibliográficos
Autores principales: Duncan, Beverly, Nazarov–Stoica, Cristina, Surls, Jacqueline, Kehl, Margaret, Bona, Constantin, Casares, Sofia, Brumeanu, Teodor-D.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2896421/
https://www.ncbi.nlm.nih.gov/pubmed/20625402
http://dx.doi.org/10.1371/journal.pone.0011427