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Double Negative (CD3(+)4(−)8(−)) TCRαβ Splenic Cells from Young NOD Mice Provide Long-Lasting Protection against Type 1 Diabetes
BACKGROUND: Double negative CD3(+)4(−)8(−) TCRαβ splenic cells (DNCD3) can suppress the immune responses to allo and xenografts, infectious agents, tumors, and some autoimmune disorders. However, little is known about their role in autoimmune diabetes, a disease characterized by the reduction of ins...
Autores principales: | Duncan, Beverly, Nazarov–Stoica, Cristina, Surls, Jacqueline, Kehl, Margaret, Bona, Constantin, Casares, Sofia, Brumeanu, Teodor-D. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2896421/ https://www.ncbi.nlm.nih.gov/pubmed/20625402 http://dx.doi.org/10.1371/journal.pone.0011427 |
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