Thioredoxin A Active-Site Mutants Form Mixed Disulfide Dimers That Resemble Enzyme–Substrate Reaction Intermediates

Thioredoxin functions in nearly all organisms as the major thiol–disulfide oxidoreductase within the cytosol. Its prime purpose is to maintain cysteine-containing proteins in the reduced state by converting intramolecular disulfide bonds into dithiols in a disulfide exchange reaction. Thioredoxin ha...

Descripción completa

Detalles Bibliográficos
Autores principales: Kouwen, Thijs R.H.M., Andréll, Juni, Schrijver, Rianne, Dubois, Jean-Yves F., Maher, Megan J., Iwata, So, Carpenter, Elisabeth P., van Dijl, Jan Maarten
Formato: Texto
Lenguaje:English
Publicado: Elsevier 2008
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2896474/
https://www.ncbi.nlm.nih.gov/pubmed/18455736
http://dx.doi.org/10.1016/j.jmb.2008.03.077

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2896474/
https://www.ncbi.nlm.nih.gov/pubmed/18455736
http://dx.doi.org/10.1016/j.jmb.2008.03.077

Ejemplares similares