The impact of intragenic CpG content on gene expression

The development of vaccine components or recombinant therapeutics critically depends on sustained expression of the corresponding transgene. This study aimed to determine the contribution of intragenic CpG content to expression efficiency in transiently and stably transfected mammalian cells. Based...

Descripción completa

Detalles Bibliográficos
Autores principales: Bauer, Asli Petra, Leikam, Doris, Krinner, Simone, Notka, Frank, Ludwig, Christine, Längst, Gernot, Wagner, Ralf
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Gene Regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2896515/
https://www.ncbi.nlm.nih.gov/pubmed/20203083
http://dx.doi.org/10.1093/nar/gkq115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2896515/
https://www.ncbi.nlm.nih.gov/pubmed/20203083
http://dx.doi.org/10.1093/nar/gkq115

Ejemplares similares