Somatic expression of LINE-1 elements in human tissues

LINE-1 expression damages host DNA via insertions and endonuclease-dependent DNA double-strand breaks (DSBs) that are highly toxic and mutagenic. The predominant tissue of LINE-1 expression has been considered to be the germ line. We show that both full-length and processed L1 transcripts are widesp...

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Detalles Bibliográficos
Autores principales: Belancio, Victoria P., Roy-Engel, Astrid M., Pochampally, Radhika R., Deininger, Prescott
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Gene Regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2896524/
https://www.ncbi.nlm.nih.gov/pubmed/20215437
http://dx.doi.org/10.1093/nar/gkq132

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2896524/
https://www.ncbi.nlm.nih.gov/pubmed/20215437
http://dx.doi.org/10.1093/nar/gkq132

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