Spt4/5 stimulates transcription elongation through the RNA polymerase clamp coiled-coil motif

Spt5 is the only known RNA polymerase-associated factor that is conserved in all three domains of life. We have solved the structure of the Methanococcus jannaschii Spt4/5 complex by X-ray crystallography, and characterized its function and interaction with the archaeal RNAP in a wholly recombinant...

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Detalles Bibliográficos
Autores principales: Hirtreiter, Angela, Damsma, Gerke E., Cheung, Alan C. M., Klose, Daniel, Grohmann, Dina, Vojnic, Erika, Martin, Andrew C. R., Cramer, Patrick, Werner, Finn
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2896526/
https://www.ncbi.nlm.nih.gov/pubmed/20197319
http://dx.doi.org/10.1093/nar/gkq135

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2896526/
https://www.ncbi.nlm.nih.gov/pubmed/20197319
http://dx.doi.org/10.1093/nar/gkq135

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