Two thymidine hydroxylases differentially regulate the formation of glucosylated DNA at regions flanking polymerase II polycistronic transcription units throughout the genome of Trypanosoma brucei

Base J is a hypermodified DNA base localized primarily to telomeric regions of the genome of Trypanosoma brucei. We have previously characterized two thymidine-hydroxylases (TH), JBP1 and JBP2, which regulate J-biosynthesis. JBP2 is a chromatin re-modeling protein that induces de novo J-synthesis, a...

Descripción completa

Detalles Bibliográficos
Autores principales: Cliffe, Laura J., Siegel, T.Nicolai, Marshall, Marion, Cross, George A. M., Sabatini, Robert
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Gene Regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2896530/
https://www.ncbi.nlm.nih.gov/pubmed/20215442
http://dx.doi.org/10.1093/nar/gkq146

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2896530/
https://www.ncbi.nlm.nih.gov/pubmed/20215442
http://dx.doi.org/10.1093/nar/gkq146

Ejemplares similares