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Ab initio gene identification in metagenomic sequences

We describe an algorithm for gene identification in DNA sequences derived from shotgun sequencing of microbial communities. Accurate ab initio gene prediction in a short nucleotide sequence of anonymous origin is hampered by uncertainty in model parameters. While several machine learning approaches...

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Detalles Bibliográficos
Autores principales: Zhu, Wenhan, Lomsadze, Alexandre, Borodovsky, Mark
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2896542/
https://www.ncbi.nlm.nih.gov/pubmed/20403810
http://dx.doi.org/10.1093/nar/gkq275