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Impact of Lentiviral Vector-Mediated Transduction on the Tightness of a Polarized Model of Airway Epithelium and Effect of Cationic Polymer Polyethylenimine

Lentiviral (LV) vectors are promising agents for efficient and long-lasting gene transfer into the lung and for gene therapy of genetically determined pulmonary diseases, such as cystic fibrosis, however, they have not been evaluated for cytotoxicity and impact on the tightness of the airway epithel...

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Detalles Bibliográficos
Autores principales: Castellani, Stefano, Di Gioia, Sante, Trotta, Teresa, Maffione, Angela Bruna, Conese, Massimo
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2896616/
https://www.ncbi.nlm.nih.gov/pubmed/20617131
http://dx.doi.org/10.1155/2010/103976