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Gene Transfer into the Lung by Nanoparticle Dextran-Spermine/Plasmid DNA Complexes
A novel cationic polymer, dextran-spermine (D-SPM), has been found to mediate gene expression in a wide variety of cell lines and in vivo through systemic delivery. Here, we extended the observations by determining the optimal conditions for gene expression of D-SPM/plasmid DNA (D-SPM/pDNA) in cell...
Autores principales: | , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2896664/ https://www.ncbi.nlm.nih.gov/pubmed/20617146 http://dx.doi.org/10.1155/2010/284840 |