Cargando…

Molecular Characterization of Heterologous HIV-1gp120 Gene Expression Disruption in Mycobacterium bovis BCG Host Strain: A Critical Issue for Engineering Mycobacterial Based-Vaccine Vectors

Mycobacterium bovis Bacillus Calmette-Guérin (BCG) as a live vector of recombinant bacterial vaccine is a promising system to be used. In this study, we evaluate the disrupted expression of heterologous HIV-1gp120 gene in BCG Pasteur host strain using replicative vectors pMV261 and pJH222. pJH222 ca...

Descripción completa

Detalles Bibliográficos
Autores principales: Joseph, Joan, Fernández-Lloris, Raquel, Pezzat, Elías, Saubi, Narcís, Cardona, Pere-Joan, Mothe, Beatriz, Gatell, Josep Maria
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2896670/
https://www.ncbi.nlm.nih.gov/pubmed/20617151
http://dx.doi.org/10.1155/2010/357370