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Cell Density Plays a Critical Role in Ex Vivo Expansion of T Cells for Adoptive Immunotherapy

The successful ex vivo expansion of a large numbers of T cells is a prerequisite for adoptive immunotherapy. In this study, we found that cell density had important effects on the process of expansion of T cells in vitro. Resting T cells were activated to expand at high cell density but failed to be...

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Detalles Bibliográficos
Autores principales: Ma, Qiangzhong, Wang, Yawen, Lo, Agnes Shuk-Yee, Gomes, Erica M., Junghans, Richard P.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2896674/
https://www.ncbi.nlm.nih.gov/pubmed/20625484
http://dx.doi.org/10.1155/2010/386545