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Cell Density Plays a Critical Role in Ex Vivo Expansion of T Cells for Adoptive Immunotherapy
The successful ex vivo expansion of a large numbers of T cells is a prerequisite for adoptive immunotherapy. In this study, we found that cell density had important effects on the process of expansion of T cells in vitro. Resting T cells were activated to expand at high cell density but failed to be...
Autores principales: | Ma, Qiangzhong, Wang, Yawen, Lo, Agnes Shuk-Yee, Gomes, Erica M., Junghans, Richard P. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2896674/ https://www.ncbi.nlm.nih.gov/pubmed/20625484 http://dx.doi.org/10.1155/2010/386545 |
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