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Conservation of mucosal associated invariant T (MAIT) cells and the MR1 restriction element in ruminants, and abundance of MAIT cells in spleen

MHC-related protein 1 (MR1) is a highly conserved MHC class I-like molecule. Human and murine mucosal associated invariant T (MAIT) cells are restricted by MR1 and express an invariant T cell receptor. Even though MR1 protein expression on the cell surface has not been demonstrated in vivo or ex viv...

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Detalles Bibliográficos
Autores principales: Goldfinch, Nick, Reinink, Peter, Connelley, Timothy, Koets, Ad, Morrison, Ivan, Van Rhijn, Ildiko
Formato: Texto
Lenguaje:English
Publicado: EDP Sciences 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2896809/
https://www.ncbi.nlm.nih.gov/pubmed/20507818
http://dx.doi.org/10.1051/vetres/2010034