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A Comprehensive In Silico Analysis of the Functional and Structural Impact of SNPs in the IGF1R Gene

Insulin-like growth factor 1 receptor (IGF1R) acts as a critical mediator of cell proliferation and survival. Many single nucleotide polymorphisms (SNPs) found in the IGF1R gene have been associated with various diseases, including both breast and prostate cancer. The genetics of these diseases coul...

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Detalles Bibliográficos
Autores principales: de Alencar, S. A., Lopes, Julio C. D.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2896858/
https://www.ncbi.nlm.nih.gov/pubmed/20625407
http://dx.doi.org/10.1155/2010/715139