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A Comprehensive In Silico Analysis of the Functional and Structural Impact of SNPs in the IGF1R Gene
Insulin-like growth factor 1 receptor (IGF1R) acts as a critical mediator of cell proliferation and survival. Many single nucleotide polymorphisms (SNPs) found in the IGF1R gene have been associated with various diseases, including both breast and prostate cancer. The genetics of these diseases coul...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Hindawi Publishing Corporation
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2896858/ https://www.ncbi.nlm.nih.gov/pubmed/20625407 http://dx.doi.org/10.1155/2010/715139 |