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Rapid cell culture and pre-clinical screening of a transforming growth factor-β (TGF-β) inhibitor for orthopaedics

BACKGROUND: Transforming growth factor-β (TGF-β) and bone morphogenetic proteins (BMPs) utilize parallel and related signaling pathways, however the interaction between these pathways in bone remains unclear. TGF-β inhibition has been previously reported to promote osteogenic differentiation in vitr...

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Detalles Bibliográficos
Autores principales: Schindeler, Aaron, Morse, Alyson, Peacock, Lauren, Mikulec, Kathy, Yu, Nicole YC, Liu, Renjing, Kijumnuayporn, Sandy, McDonald, Michelle M, Baldock, Paul A, Ruys, Andrew J, Little, David G
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2896919/
https://www.ncbi.nlm.nih.gov/pubmed/20509926
http://dx.doi.org/10.1186/1471-2474-11-105