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Transcriptomic responses in mouse brain exposed to chronic excess of the neurotransmitter glutamate

BACKGROUND: Increases during aging in extracellular levels of glutamate (Glu), the major excitatory neurotransmitter in the brain, may be linked to chronic neurodegenerative diseases. Little is known about the molecular responses of neurons to chronic, moderate increases in Glu levels. Genome-wide g...

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Detalles Bibliográficos
Autores principales: Wang, Xinkun, Bao, Xiaodong, Pal, Ranu, Agbas, Abdulbaki, Michaelis, Elias K
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2896956/
https://www.ncbi.nlm.nih.gov/pubmed/20529287
http://dx.doi.org/10.1186/1471-2164-11-360