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Crystal structure and ligand binding of the MID domain of a eukaryotic Argonaute protein
Argonaute (AGO) proteins are core components of RNA-induced silencing complexes and have essential roles in RNA-mediated gene silencing. They are characterized by a bilobal architecture, consisting of one lobe containing the amino-terminal and PAZ domains and another containing the MID and PIWI doma...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2897117/ https://www.ncbi.nlm.nih.gov/pubmed/20539312 http://dx.doi.org/10.1038/embor.2010.81 |