Cargando…

Crystal structure and ligand binding of the MID domain of a eukaryotic Argonaute protein

Argonaute (AGO) proteins are core components of RNA-induced silencing complexes and have essential roles in RNA-mediated gene silencing. They are characterized by a bilobal architecture, consisting of one lobe containing the amino-terminal and PAZ domains and another containing the MID and PIWI doma...

Descripción completa

Detalles Bibliográficos
Autores principales:	Boland, Andreas, Tritschler, Felix, Heimstädt, Susanne, Izaurralde, Elisa, Weichenrieder, Oliver
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2010
Materias:	Scientific Reports
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2897117/ https://www.ncbi.nlm.nih.gov/pubmed/20539312 http://dx.doi.org/10.1038/embor.2010.81

Ejemplares similares

The RRM domain in GW182 proteins contributes to miRNA-mediated gene silencing
por: Eulalio, Ana, et al.
Publicado: (2009)

The C-terminal α–α superhelix of Pat is required for mRNA decapping in metazoa
por: Braun, Joerg E, et al.
Publicado: (2010)

Crystal structure and functional properties of the human CCR4-CAF1 deadenylase complex
por: Chen, Ying, et al.
Publicado: (2021)

Two PABPC1-binding sites in GW182 proteins promote miRNA-mediated gene silencing
por: Huntzinger, Eric, et al.
Publicado: (2010)

Relating protein crystal structure to ligand-binding thermodynamics
por: Helliwell, John R.
Publicado: (2022)

A conserved CAF40-binding motif in metazoan NOT4 mediates association with the CCR4–NOT complex
por: Keskeny, Csilla, et al.
Publicado: (2019)

Structural basis for the Nanos-mediated recruitment of the CCR4–NOT complex and translational repression
por: Bhandari, Dipankar, et al.
Publicado: (2014)

A CAF40-binding motif facilitates recruitment of the CCR4-NOT complex to mRNAs targeted by Drosophila Roquin
por: Sgromo, Annamaria, et al.
Publicado: (2017)

Effects of the PIWI/MID domain of Argonaute protein on the association of miRNAi's seed base with the target
por: Wang, Zhen, et al.
Publicado: (2019)

Mextli proteins use both canonical bipartite and novel tripartite binding modes to form eIF4E complexes that display differential sensitivity to 4E-BP regulation
por: Peter, Daniel, et al.
Publicado: (2015)

Distinct modes of recruitment of the CCR4–NOT complex by Drosophila and vertebrate Nanos
por: Raisch, Tobias, et al.
Publicado: (2016)

Drosophila Bag-of-marbles directly interacts with the CAF40 subunit of the CCR4–NOT complex to elicit repression of mRNA targets
por: Sgromo, Annamaria, et al.
Publicado: (2018)

Mammalian Argonaute-DNA binding?
por: Smalheiser, Neil R, et al.
Publicado: (2014)

Binding-induced functional-domain motions in the Argonaute characterized by adaptive advanced sampling
por: Pourjafar-Dehkordi, Danial, et al.
Publicado: (2021)

The structural basis for the interaction between the CAF1 nuclease and the NOT1 scaffold of the human CCR4–NOT deadenylase complex
por: Petit, Alain-Pierre, et al.
Publicado: (2012)

PICK1 links Argonaute 2 to endosomes in neuronal dendrites and regulates miRNA activity
por: Antoniou, Anna, et al.
Publicado: (2014)

HPat provides a link between deadenylation and decapping in metazoa
por: Haas, Gabrielle, et al.
Publicado: (2010)

Assembly and analysis of eukaryotic Argonaute–RNA complexes in microRNA-target recognition
por: Gan, Hin Hark, et al.
Publicado: (2015)

Ligand Binding and Crystal Structures of the Substrate-Binding Domain of the ABC Transporter OpuA
por: Wolters, Justina C., et al.
Publicado: (2010)

Domain motions of Argonaute, the catalytic engine of RNA interference
por: Ming, Dengming, et al.
Publicado: (2007)

RNA binding by Hfq and ring-forming (L)Sm proteins: A trade-off between optimal sequence readout and RNA backbone conformation
por: Weichenrieder, Oliver
Publicado: (2014)

The Argonaut
Publicado: (1890)

The crystal structure of the catalytic domain of a eukaryotic guanylate cyclase
por: Winger, Jonathan A, et al.
Publicado: (2008)

Mid-Range Inhomogeneity of Eukaryotic Genomes
por: Fedorova, Larisa, et al.
Publicado: (2011)

Rewiring of PDZ Domain-Ligand Interaction Network Contributed to Eukaryotic Evolution
por: Kim, Jinho, et al.
Publicado: (2012)

Expanded RNA-binding activities of mammalian Argonaute 2
por: Tan, Grace S., et al.
Publicado: (2009)

AGODB: a comprehensive domain annotation database of argonaute proteins
por: Li, Bowen, et al.
Publicado: (2022)

Argonaute and Argonaute-Bound Small RNAs in Stem Cells
por: Zhai, Lihong, et al.
Publicado: (2016)

Phosphorylation of human Argonaute proteins affects small RNA binding
por: Rüdel, Sabine, et al.
Publicado: (2011)

Thermodynamic characterization of an engineered tetracycline-binding riboswitch
por: Müller, Michael, et al.
Publicado: (2006)

The evolution of animal Argonautes: evidence for the absence of antiviral AGO Argonautes in vertebrates
por: Wynant, Niels, et al.
Publicado: (2017)

Modeling the binding of diverse ligands within the Ah receptor ligand binding domain
por: Giani Tagliabue, Sara, et al.
Publicado: (2019)

Control of hepatic gluconeogenesis by Argonaute2
por: Yan, Xin, et al.
Publicado: (2018)

Mechanistic Insights into Archaeal and Human Argonaute Substrate Binding and Cleavage Properties
por: Willkomm, Sarah, et al.
Publicado: (2016)

Robotic Versus Laparoscopic Resection for Mid and Low Rectal Cancers
por: Bedirli, Abdulkadir, et al.
Publicado: (2016)

The Argonaute protein family
por: Höck, Julia, et al.
Publicado: (2008)

Targeting Argonaute to chromatin
por: Wendte, Jered M., et al.
Publicado: (2016)

A genetic system to assess in vivo the functions of histones and histone modifications in higher eukaryotes
por: Günesdogan, Ufuk, et al.
Publicado: (2010)

Identification and phylogenetic analyses of VASt, an uncharacterized protein domain associated with lipid-binding domains in Eukaryotes
por: Khafif, Mehdi, et al.
Publicado: (2014)

The PAM domain, a multi-protein complex-associated module with an all-alpha-helix fold
por: Ciccarelli, Francesca D, et al.
Publicado: (2003)

Cannot write session to /tmp/vufind_sessions/sess_306imp0ijc50ptmoha6j1m72q7