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A classification model for distinguishing copy number variants from cancer-related alterations

BACKGROUND: Both somatic copy number alterations (CNAs) and germline copy number variants (CNVs) that are prevalent in healthy individuals can appear as recurrent changes in comparative genomic hybridization (CGH) analyses of tumors. In order to identify important cancer genes CNAs and CNVs must be...

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Detalles Bibliográficos
Autores principales: Ostrovnaya, Irina, Nanjangud, Gouri, Olshen, Adam B
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2897829/
https://www.ncbi.nlm.nih.gov/pubmed/20525196
http://dx.doi.org/10.1186/1471-2105-11-297