A novel chemogenomics analysis of G protein-coupled receptors (GPCRs) and their ligands: a potential strategy for receptor de-orphanization

BACKGROUND: G protein-coupled receptors (GPCRs) represent a family of well-characterized drug targets with significant therapeutic value. Phylogenetic classifications may help to understand the characteristics of individual GPCRs and their subtypes. Previous phylogenetic classifications were all bas...

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Detalles Bibliográficos
Autores principales: van der Horst, Eelke, Peironcely, Julio E, IJzerman, Adriaan P, Beukers, Margot W, Lane, Jonathan R, van Vlijmen, Herman WT, Emmerich, Michael TM, Okuno, Yasushi, Bender, Andreas
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2897831/
https://www.ncbi.nlm.nih.gov/pubmed/20537162
http://dx.doi.org/10.1186/1471-2105-11-316

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2897831/
https://www.ncbi.nlm.nih.gov/pubmed/20537162
http://dx.doi.org/10.1186/1471-2105-11-316

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