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Specific Humoral Immunity versus Polyclonal B Cell Activation in Trypanosoma cruzi Infection of Susceptible and Resistant Mice

BACKGROUND: The etiologic agent of Chagas Disease is Trypanosoma cruzi. Acute infection results in patent parasitemia and polyclonal lymphocyte activation. Polyclonal B cell activation associated with hypergammaglobulinemia and delayed specific humoral immunity has been reported during T. cruzi infe...

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Detalles Bibliográficos
Autores principales: Bryan, Marianne A., Guyach, Siobhan E., Norris, Karen A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2897841/
https://www.ncbi.nlm.nih.gov/pubmed/20625554
http://dx.doi.org/10.1371/journal.pntd.0000733