CD40 Ligand (CD154) Incorporated into HIV Virions Induces Activation-Induced Cytidine Deaminase (AID) Expression in Human B Lymphocytes

Most AIDS-associated non-Hodgkin's lymphoma (AIDS-NHL) arises from errors in immunoglobulin heavy-chain gene (IgH) class switch recombination (CSR) or somatic hypermutation (SHM), events that occur in germinal center (GC) B cells and require the activity of activation induced cytidine deaminase...

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Detalles Bibliográficos
Autores principales: Epeldegui, Marta, Thapa, Dharma R., De La Cruz, Justin, Kitchen, Scott, Zack, Jerome A., Martínez-Maza, Otoniel
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2897846/
https://www.ncbi.nlm.nih.gov/pubmed/20625427
http://dx.doi.org/10.1371/journal.pone.0011448

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2897846/
https://www.ncbi.nlm.nih.gov/pubmed/20625427
http://dx.doi.org/10.1371/journal.pone.0011448

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