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CD40 Ligand (CD154) Incorporated into HIV Virions Induces Activation-Induced Cytidine Deaminase (AID) Expression in Human B Lymphocytes
Most AIDS-associated non-Hodgkin's lymphoma (AIDS-NHL) arises from errors in immunoglobulin heavy-chain gene (IgH) class switch recombination (CSR) or somatic hypermutation (SHM), events that occur in germinal center (GC) B cells and require the activity of activation induced cytidine deaminase...
Autores principales: | Epeldegui, Marta, Thapa, Dharma R., De La Cruz, Justin, Kitchen, Scott, Zack, Jerome A., Martínez-Maza, Otoniel |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2897846/ https://www.ncbi.nlm.nih.gov/pubmed/20625427 http://dx.doi.org/10.1371/journal.pone.0011448 |
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