Cargando…

Dendritic Cells in Chronic Mycobacterial Granulomas Restrict Local Anti-Bacterial T Cell Response in a Murine Model

BACKGROUND: Mycobacterium-induced granulomas are the interface between bacteria and host immune response. During acute infection dendritic cells (DCs) are critical for mycobacterial dissemination and activation of protective T cells. However, their role during chronic infection in the granuloma is p...

Descripción completa

Detalles Bibliográficos
Autores principales: Schreiber, Heidi A., Hulseberg, Paul D., Lee, JangEun, Prechl, Jozsef, Barta, Peter, Szlavik, Nora, Harding, Jeffrey S., Fabry, Zsuzsanna, Sandor, Matyas
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2897891/
https://www.ncbi.nlm.nih.gov/pubmed/20625513
http://dx.doi.org/10.1371/journal.pone.0011453