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Modeling non-uniformity in short-read rates in RNA-Seq data
After mapping, RNA-Seq data can be summarized by a sequence of read counts commonly modeled as Poisson variables with constant rates along each transcript, which actually fit data poorly. We suggest using variable rates for different positions, and propose two models to predict these rates based on...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2898062/ https://www.ncbi.nlm.nih.gov/pubmed/20459815 http://dx.doi.org/10.1186/gb-2010-11-5-r50 |