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Evidence for natural antisense transcript-mediated inhibition of microRNA function

BACKGROUND: MicroRNAs (miRNAs) have the potential to regulate diverse sets of mRNA targets. In addition, mammalian genomes contain numerous natural antisense transcripts, most of which appear to be non-protein-coding RNAs (ncRNAs). We have recently identified and characterized a highly conserved non...

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Detalles Bibliográficos
Autores principales: Faghihi, Mohammad Ali, Zhang, Ming, Huang, Jia, Modarresi, Farzaneh, Van der Brug, Marcel P, Nalls, Michael A, Cookson, Mark R, St-Laurent, Georges, Wahlestedt, Claes
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2898074/
https://www.ncbi.nlm.nih.gov/pubmed/20507594
http://dx.doi.org/10.1186/gb-2010-11-5-r56