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Distinct Biological Network Properties between the Targets of Natural Products and Disease Genes
[Image: see text] We show that natural products target proteins with a high number of protein−protein functional interactions (high biological network connectivity) and that these protein targets have higher network connectivity than disease genes. This feature may facilitate disruption of essential...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2898216/ https://www.ncbi.nlm.nih.gov/pubmed/20565092 http://dx.doi.org/10.1021/ja102798t |