A Single Residue Switch for Mg(2+)-dependent Inhibition Characterizes Plant Class II Diterpene Cyclases from Primary and Secondary Metabolism

Class II diterpene cyclases mediate the acid-initiated cycloisomerization reaction that serves as the committed step in biosynthesis of the large class of labdane-related diterpenoid natural products, which includes the important gibberellin plant hormones. Intriguingly, these enzymes are differenti...

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Detalles Bibliográficos
Autores principales: Mann, Francis M., Prisic, Sladjana, Davenport, Emily K., Determan, Mara K., Coates, Robert M., Peters, Reuben J.
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2010
Materias:
Enzymology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2898348/
https://www.ncbi.nlm.nih.gov/pubmed/20430888
http://dx.doi.org/10.1074/jbc.M110.123307

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2898348/
https://www.ncbi.nlm.nih.gov/pubmed/20430888
http://dx.doi.org/10.1074/jbc.M110.123307

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