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Glycosylation Patterns of HIV-1 gp120 Depend on the Type of Expressing Cells and Affect Antibody Recognition

Human immunodeficiency virus type 1 (HIV-1) entry is mediated by the interaction between a variably glycosylated envelope glycoprotein (gp120) and host-cell receptors. Approximately half of the molecular mass of gp120 is contributed by N-glycans, which serve as potential epitopes and may shield gp12...

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Detalles Bibliográficos
Autores principales: Raska, Milan, Takahashi, Kazuo, Czernekova, Lydie, Zachova, Katerina, Hall, Stacy, Moldoveanu, Zina, Elliott, Matt C., Wilson, Landon, Brown, Rhubell, Jancova, Dagmar, Barnes, Stephen, Vrbkova, Jana, Tomana, Milan, Smith, Phillip D., Mestecky, Jiri, Renfrow, Matthew B., Novak, Jan
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2898351/
https://www.ncbi.nlm.nih.gov/pubmed/20439465
http://dx.doi.org/10.1074/jbc.M109.085472