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Induced-fit Mechanism for Prolyl Endopeptidase

Prolyl peptidases cleave proteins at proline residues and are of importance for cancer, neurological function, and type II diabetes. Prolyl endopeptidase (PEP) cleaves neuropeptides and is a drug target for neuropsychiatric diseases such as post-traumatic stress disorder, depression, and schizophren...

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Detalles Bibliográficos
Autores principales: Li, Min, Chen, Changqing, Davies, David R., Chiu, Thang K.
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2898448/
https://www.ncbi.nlm.nih.gov/pubmed/20444688
http://dx.doi.org/10.1074/jbc.M109.092692