Midkine inhibitors: application of a simple assay procedure to screening of inhibitory compounds

BACKGROUND: Midkine is a heparin-binding cytokine and is involved in etiology of various diseases. Thus, midkine inhibitors are expected to be helpful in treatment of many diseases. METHODS: We developed a simple assay for midkine activity based on midkine-dependent migration of osteblastic cells. M...

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Detalles Bibliográficos
Autores principales: Matsui, Takashi, Ichihara-Tanaka, Keiko, Lan, Chen, Muramatsu, Hisako, Kondou, Toshiharu, Hirose, Chizuru, Sakuma, Sadatoshi, Muramatsu, Takashi
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2898662/
https://www.ncbi.nlm.nih.gov/pubmed/20565917
http://dx.doi.org/10.1186/1755-7682-3-12

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2898662/
https://www.ncbi.nlm.nih.gov/pubmed/20565917
http://dx.doi.org/10.1186/1755-7682-3-12

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